Osteoporosis is a disease of the bones that leads to an increased risk of fracture through the weakening of the bones. This occurs due to a reduction in the bone mineral density, deterioration of the bone micro architecture and alteration in the number and types of proteins in the bone.
Post menopausal Osteoporosis and senile Osteoporosis are the common varieties seen in people. Senile osteoporosis affects women in the ratio of 2:1 compared to men. Over two million women in the UK have Osteoporosis.
Osteoporosis is diagnosed by doing a bone density scan also called DEXA scan (dual energy X-ray absorptiometry). Osteoporosis is defined by the World Health Organization as a bone mineral density that is 2.5 standard deviations or more below the mean peak bone mass (average of young, healthy adults) as measured by DEXA scan.
Osteoporosis in itself does not cause any symptoms. It increases the risk of sustaining a fracture, especially in the wrist, hip and spine. This can lead to pain and other problems like loss of mobility and independence.
We have done over 15 clinical trials in Osteoporosis in the last 10 years, recruiting several hundred patients into different studies. We are well equipped with a HOLOGIC bone density scanner capable of doing hip, spine and whole body DEXA scan. Some of the investigational products we were involved with have been licensed for use in the recent years and our patients have had the benefit of continuing on the new block buster drugs.
We have conducted mass screening program to identify patients with Osteoporosis who have either benefitted by participating in trials or having been treated by their GP’s. We also do the scans for patients referred by the NHS. MeDiNova has significant experience of both female and male Osteoporosis studies.